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Index > Protein center > SPARC(Gene name) > Bovine
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  • SPARC (Gene name),
  • SPARC (Protein name ),  SPRC_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    SPARC;
    Protein name:
    SPARC;
    Alternative:
    Osteonectin(ON);Basement-membrane protein 40(BM-40);Secreted protein acidic and rich in cysteine;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
    Subcellular Location:
    Secreted extracellular space extracellular matrix basement membrane In or around the basement membrane.
    Protein Attributes:
    Sequence length:
    303
    Sequence:
    50:
    MRAWIFFLLC | LAGRALAAPQ | QEALPDETEV | VEETVAEVAE | VPVGANPVQV | 
    100:
    EVGEFDDGAE | ETEEEVVAEN | PCQNHHCKHG | KVCELDENNT | PMCVCQDPTS | 
    150:
    CPAPIGEFEK | VCSNDNKTFD | SSCHFFATKC | TLEGTKKGHK | LHLDYIGPCK | 
    200:
    YIPPCLDSEL | TEFPLRMRDW | LKNVLVTLYE | RDEDNNLLTE | KQKLRVKKIH | 
    250:
    ENEKRLEAGD | HPVELLARDF | EKNYNMYIFP | VHWQFGQLDQ | HPIDGYLSHT | 
    300:
    ELAPLRAPLI | PMEHCTTRFF | ETCDLDNDKY | IALDEWAGCF | GIKEKDIDKD | 
    303:
    LVI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine SPARC
    Cat.:
    E0791h
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    96T
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    ELISA Kit for Bovine SPARC
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    E0791m
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    96T
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    ELISA Kit for Bovine SPARC
    Cat.:
    E0791r
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    96T
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    ELISA Kit for Bovine SPARC
    Cat.:
    E0791b
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    96T
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    ELISA Kit for Bovine SPARC
    Cat.:
    E0791p
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    96T
    ELISA Kit for Bovine SPARC
    Cat.:
    E0791c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine SPARC
    MSDS:
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    CLIA Kit for Bovine SPARC
    Cat.:
    U0791b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine SPARC
    Cat.:
    U0791p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine SPARC
    Cat.:
    U0791c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine SPARC
    Cat.:
    U0791r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Bovine SPARC
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine SPARC
    Cat.:
    U0791m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine SPARC
    Cat.:
    U0791h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Bovine SPARC
    Polyclonal Antibody for Bovine SPARC
    Cat.:
    P0791Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine SPARC
    Polyclonal Antibody for Bovine SPARC
    Polyclonal Antibody for Bovine SPARC
    Cat.:
    P0791Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine SPARC
    Polyclonal Antibody for Bovine SPARC
    Cat.:
    P0791Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Monoclonal Antibody for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC
    Protein for Bovine SPARC

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    References
    1. 1.
      "Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid)."
      Bolander M.E. , Young M.F. , Fisher L.W. , Yamada Y. , Termine J.D.
      Proc. Natl. Acad. Sci. U.S.A.85:2919-2923(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal liver.
    4. 4.
      "Isolation of the osteonectin gene: evidence that a variable region of the osteonectin molecule is encoded within one exon."
      Findlay D.M. , Fisher L.W. , McQuillan C.I. , Termine J.D. , Young M.F.
      Biochemistry27:1483-1489(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-69
    5. 5.
      "Osteonectin mRNA: distribution in normal and transformed cells."
      Young M.F. , Bolander M.E. , Day A.A. , Ramis C.I. , Robey P.G. , Yamada Y. , Termine J.D.
      Nucleic Acids Res.14:4483-4497(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 18-36
    6. 6.
      "Characterization of porcine osteonectin extracted from foetal calvariae."
      Domenicucci C. , Goldberg H.A. , Hofmann T. , Isenman D. , Wasi S. , Sodek J.
      Biochem. J.253:139-151(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-55;CHARACTERIZATION
    7. 7.
      "Isolation and characterization of native adult osteonectin."
      Romberg R.W. , Werness P.G. , Lollar P. , Riggs B.L. , Mann K.G.
      J. Biol. Chem.260:2728-2736(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-36;CALCIUM-BINDING;SUBCELLULAR LOCATION;CHARACTERIZATION
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